Stephen Hughes

Job Role
Visiting Professor in Biomedical Science
North Wales Clinical Research Centre


I am employed by Betsi Cadwaladr University Health Board (BCUHB) as a Consultant Biomedical Scientist & Director of the Maelor Academic Unit of Medical & Surgical Sciences (MAUMSS). MAUMSS is the main vehicle for my current research work, which primarily involves investigating patients with benign or malignant disorders of the kidneys, bladder and prostate.

I am a Fellow Member of the Institute of Biomedical Science (IBMS) and a Chartered Scientist (CSci) affiliated with the Science Council. During my career, I have worked as a Health & Care Professions Council (HCPC) registered Biomedical Scientist (Haematology with Hospital Transfusion Practice) for the NHS, and as Senior Biomedical Scientist and Pathology Manager at the North Wales Medical Centre.

Amongst my various external activities, I am a Specialist Portfolio Examiner for the IBMS. This role involves assessing the suitability of hospital based practitioners to practice at a Senior Scientist or Managerial level. I am an IBMS Academic Accreditation Panel Member at national level. This role enables me to identify and implement curriculum change to programmes at other Higher Education Institutions (HEI). I am also a Scientific Advisor for British Urology Researchers in Surgical Training (BURST).

By invitation, I have been External Examiner for Keele University (MSc Blood Sciences), Nottingham Trent University and the University of Wolverhampton. I am also a Fellow Member of the Higher Education Academy (FHEA).

I possess a wide range of laboratory experience in the biomedical research and teaching fields, and I am skilled in various immuno-haematological and biochemistry techniques.

Outside of work, I enjoy spending time with my family and friends and playing golf.


Qualifications: BSc (Hons), PgCert, MPhil, PhD

Professional: FIBMS, CSci, FRSB, FHEA


Specifically, my current research interests are divided into the following areas:



•Kidney stones

•Benign and malignant disorders of the bladder

•Benign and malignant disorders of the prostate

•Clinical outcome measures (e.g. acute kidney injury, infection and bleeding) and their relationship with biomarkers



•Leukocyte biology

•Vascular endothelium


•Metastasis and cancer recurrence

•Cytokines & adhesion molecules

•Novel biomarkers and diagnostics


Key Collaborators

Prof Steve Conlan (Swansea University)

Prof Andrew Tee (Cardiff University)

Prof Luis Mur (Aberystwyth University)

Prof Leandro Pecchia (University of Warwick)





Blood Sciences

Clinical Medicine: Pathology of disease

Research Methods



Hughes, S.F., Jones, N., Thomas-Wright, S.J. et al. (2020). Shock wave lithotripsy, for the treatment of kidney stones, results in changes to routine blood tests and novel biomarkers: a prospective clinical pilot-study. Eur J Med Res 25, 18.

Castaldo R., Hughes S.F., et al. (2020) Investigating the Use of Wearables for Monitoring Circadian Rhythms: A Feasibility Study. In: Lin KP., Magjarevic R., de Carvalho P. (eds) Future Trends in Biomedical and Health Informatics and Cybersecurity in Medical Devices. ICBHI 2019. IFMBE Proceedings, vol 74. Springer, Cham.

Dobbin, N., Bloyce, D., Hughes, S.F. et al. (2020). Effects of a 4 week touch rugby and self-paced interval running intervention on health markers in active young men. Sport Sci Health

Bell, C., Moore, S.L., Gill, A., Hughes, S.F. et al. (2019). Safety and efficacy of Holmium laser enucleation of the prostate (HoLEP) in patients with previous transperineal biopsy (TPB): outcomes from a dual-centre case-control study. BMC Urol 19, 97.

Moyes, A. J., Lamb, R. M., Ella-Tongwiis, P., Pushkaran, A., Ahmed, I., Shergill, I., & Hughes, S. F. (2017). A pilot study evaluating changes to haematological and biochemical tests after Flexible Ureterorenoscopy for the treatment of kidney stones. PloS one12(7), e0179599.

Agbalalah T, Hughes SF, Freeborn EJ, Mushtaq S. (2017). Impact of vitamin D supplementation on endothelial and inflammatory markers in adults: A systematic review. J Steroid Biochem Mol Biol.;173:292-300. https://doi:10.1016/j.jsbmb.2017.01.015.